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Three-terminal transcriptor-based gates use integrase (Int) control signals to modulate RNA polymerase flow between a separate gate input and output (credit: Bonnet et al./Science)

Stanford University bioengineers have taken computing beyond mechanics and electronics into the living realm of biology by creating the “transcriptor” — a biological transistor made from DNA and RNA.

In electronics, a transistor controls the flow of electrons along a circuit. Similarly, a transcriptor controls the flow of a specific protein, RNA polymerase, as it travels along a strand of DNA.

“Transcriptors are the…

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